Table 1. Picard alignment summary metrics.

Summary of the sequencing and mapping of the data to the B. malayi transcriptome.

	Time point	Concentration	Total # Transcripts	Ave Total # Reads	Ave Total # Reads Mapped	Ave Total # High Quality Reads Mapped	% High Quality Reads Mapped
Study 1	24 h	IVM (100 nM)	10691	3537601	3537500	2990362	84.53
		Control	10511	2765626	2765551	2364245	85.49
	48 h	IVM (100 nM)	10086	2513891	2513834	2145661	85.35
		Control	10214	2957918	2957831	2519799	85.19
	72 h	IVM (100 nM)	10705	3875640	3874592	3380930	87.24
		Control	10428	3081545	3081499	2683543	87.09
Study 2	48 h	IVM (300 nM)	10087	2091222	2091198	1710598	81.80
		IVM (1 μM)	10177	2212133	2212085	1757015	79.43
		Control	10328	2808908	2808880	2325764	82.80
	5 d	IVM (300 nM)	9959	1799180	1799161	1456538	80.96
		IVM (1 μM)	9837	1798183	1798159	1426230	79.32
		Control	10250	2464701	2464671	2017612	81.86