Table 2. Numbers of differentially expressed genes over time after IVM exposure in culture.

	100 nM IVM			300 nM IVM		1 μM IVM
	24 h	48 h	72 h	48 h	5 d	48 h	5 d
Total DE genes	34	421	15	132	68	147	271
Total DE genes up-regulated	21	141	2	14	24	136	74
Total DE genes down-regulated	13	280	13	118	44	11	197
Sequences with GO terms*	7	178	9	86	29	49	160
Sequences with C. elegans ortholog	7	257	9	92	37	64	186

*GO terms were provided by Nematode.net V.4 [33]. IVM: ivermectin; DE: differentially expressed