Table 2. Attributable adverse events are grouped by route of administration (Upper gastrointestinal routes; Lower gastrointestinal routes).

First Author, Year (Ref.)	AEs	The number of patients with AEs	Sample size	Causality between AEs and FMT	Routes of infusion
Upper gastrointestinal routes
Vermeire, 2012 [60]	Fever; Abdominal tenderness	3	4	Probably	Nasojejunal tube
Cui, 2014 [41]	Fever; Increased diarrhea	7	30	Probably	Gastroscopy (mid-gut)
Van Nood, 2013 [61]	Belching; Nausea; Abdominal cramps; Diarrhea; Abdominal pain; Infection; Dizziness combined with diarrhea; Constipation	27	29	Probably	Nasoduodenal tube
Aas, 2003 [62]	Death from peritonitis	1	18	Possibly	Nasogastric tube
MacConnachie, 2009 [42]	Upper gastrointestinal hemorrhage	1	15	Possibly	Nasogastric tube
Kronman, 2015 [63]	Vomiting; Mucoid stools	1	10	Probably	Nasogastric, nasoduodenal or nasojejunal tube
Pinn, 2014 [26]	Flatulence	1	13	Probably	Esophagogastroduodenoscopy
Wang, 2013 [64]	Diarrhea	5	16	Probably	Gastroscopy
Suskind, 2015 [65]	Rhinorrhea; Sore throat	5	9	Definitely	Nasogastric tube
	Abdominal pain; Bloating; Diarrhea; Flatulence			Probably
Suskind, 2015 [66]	Nasal stuffiness; Flatulence	1	4	Probably	Nasogastric tube
	Bloating			Possibly
Rossen, 2015 [50]	Discomfort tube placement; Fever; Nausea; Malaise; Increase of stool frequency/diarrhea; Headache; Vomited fecal infusion; Vomited bowel prep; Vomiting; Abdominal cramps; Abdominal pain; Abdominal murmurs; Dizziness; Mild constipation	34	48	Probably	Nasoduodenal tube
Borody, 2003 [67]	Sore throat	3	8	Definitely	Nasojejunal tube
Lower gastrointestinal routes
Kump, 2013 [68]	Fever; Temporary increase of CRP and IL-6; Increase in stool frequency	1	6	Probably	Colonoscopy
Zhang, 2013 [69]	Severe cold	1	1	Possibly	Colonoscopy
Quera, 2013 [44]	Fever; Bacteremia	1	1	Probably	Colonoscopy
Kunde, 2013 [70]	Fever; Chills; Abdominal fullness	2	10	Probably	Enema
	UC flare			Possibly
Gustafsson, 1998 [71]	Diarrhea	3	9	Probably	Enema
Lee, 2014 [72]	Transient constipation; Excess flatulence	9	94	Probably	Enema
Hamilton, 2012 [73]	Irregularity of bowel movements; Excessive flatulence	14	43	Probably	Colonoscopy
Khoruts, 2010 [74]	Constipation; Irregularity of bowel movements	1	1	Probably	Colonoscopy
Pierog, 2014 [75]	Appendicitis	1	6	Possibly	Colonoscopy
Silverman, 2010 [76]	Urinary tract infections	2	7	Possibly	Enema
Hohmann, 2014 [39]	Cytomegalovirus colitis	1	1	Probably	Enema
De Leon, 2013 [40]	Transient relapse of UC	1	1	Probably	Colonoscopy
Schwartz, 2013 [43]	Norovirus Gastroenteritis	1	13	Probably	Colonoscopy
Brandt, 2012 [20]	Peripheral neuropathy; Sjogren’s disease; Idiopathic Thrombocytopenic purpura; Rheumatoid arthritis	4	77	Possibly	Colonoscopy
Mellow, 2011 [77]	Relapse of CDI	1	13	Possibly	Colonoscopy
Mandalia, 2014[78]	Diverticulitis; Fever	1	1	Probably	Colonoscopy
Dutta, 2014 [79]	Fever; Bloating	5	27	Probably	Enteroscopy and colonoscopy
Ray, 2014 [80]	Pain/nausea; Bloating/cramps; Gas/nausea	4	20	Probably	Colonoscopy
	Continuing diarrhea			Possibly
Satokari, 2015 [53]	Mild transient fever	2	49	Probably	Colonoscopy
Sun, 2014 [45]	Multi-organism bacteremia	1	1	Probably	Colonoscopy
Mandalia, 2014 [81]	Abdominal pain	1	29	Probably	Colonoscopy
Cammarota, 2015 [49]	Diarrhea; Bloating and abdominal cramping	19	20	Probably	Colonoscopy