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. 2016 Aug 16;11(8):e0160915. doi: 10.1371/journal.pone.0160915

Fig 2. miR-200c modulates proinflammatory mediators in human preosteoblasts.

Fig 2

A and B: the transcripts of IL-6 (A) and IL-8 (B) in non-treated HEPM cells and the cells with miR-200c or scrambled miRs cultured in DMEM supplemented with LPS at 0, 1, 5 and 10 μg/mL after 24 hours; *:p<0.05 vs non-treated; C: the amounts of IL-8 secreted by HEPM cells with miR-200c or scrambled miRs cultured in DMEM supplemented with or without LPS at different time points; *: p<0.05 vs cells with scrambled miRs; D and E: the amounts of IL-6 (D) and CCL-5 (E) secreted by HEPM cells with miR-200c or scrambled miRs cultured in DMEM supplemented with or without LPS after 24 hrs; F: the amounts of OPG secreted by HEPM cells with different miRs cultured in DMEM supplemented with or without LPS after 32 hours. *: p<0.05.