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Relative arm usage changes in microRNAs. Comparisons of the relative strand usage of P. tepidariorum microRNAs to ( A ) T. castaneum and ( B ) D. melanogaster show microRNAs that have undergone strand switching in the 3′/5′ and 5′/3′ quadrants. The dashed line indicates the theoretical expectation for conserved arm usage between the two species. Dotted lines limit the boundaries of the dashed line to less than 10-fold differences in arm usage.
