Table.
Clinical characteristics of HIV/HCV co-infected and HIV mono infected patients
| Characteristics | HIV/HCV co-infected | HIV monoinfected | Uninfected |
|---|---|---|---|
|
| |||
| 1 | 2 | 3 | |
| Examined subjects (n) | 42 | 37 | 20 |
| Age (years) | 33 (32/37)• | 34 (31/41) | 31 (26/35) |
| Male | 26 (61.9%) | 8 (21.6%) | 8 (40.0%) |
| HIV transmission route | |||
| Intravenous | 36 (85.7%) | 1 (2.7%) | – |
| Sexual | 6 (14.3%) | 36 (97.3%) | – |
| Homosexuals | 0 | 0 | 0 |
| Sex workers | 0 | 0 | 0 |
| Active drug users | 0 | 0 | 0 |
| HIV infection characteristics | |||
| Infection duration (years) | 11 (9/12) P1-2<0.001 |
8 (6/10) | – |
| HAART duration (years) | 3.5 (2/5) P1-2>0.05 |
4 (3/5) | – |
| Nadir CD4+ T cell count (μl−1) | 140 (100/170) P1-2>0.05 |
150 (106/170) | – |
| CD4+ T cells at the study (μl−1) | 350 (260/450) P1-2>0.05 |
410 (290/570) P2-3<0.001 |
1050 (660/1280) P1-3<0.001 |
| HIV viral load (copies/ml) | < 50 | < 50 | – |
| HCV infection characteristics | |||
| Infection duration (years) | 11 (8/12) | – | – |
| HCV viral load (log10 copies/ml) | 6.21 (2.88/6.59) | < 2,88 | < 2,88 |
| AST (U/l) | 47 (29/75) P1-2<0.001 |
19 (17/23) P2-3>0.05 |
19 (15/24) P1-3<0.001 |
| ALT (U/l) | 59 (28/112) P1-2<0.001 |
18 (14/23) P2-3>0.05 |
19 (15/26) P1-3<0.001 |
| γ-GT (U/l) | 71 (35/122) P1-2<0.001 |
30 (23/45) P2-3>0.05 |
27 (21/34) P1-3<0.001 |
| albumin (g/l) | 41.7 (40.9/42.5) P1-2>0.05 |
41.3 (40.4/43.5) P2-3>0.05 |
41.8 (40.8/42.6) P1-3>0.05 |
| platelets (109/l) | 202 (167/244) P1-2>0.05 |
234 (177/276) | – |
| APRI | 0.6 (0.4/1.2) P1-2<0.001 |
0.2 (0.2/0.3) | – |
AST – aspartate aminotransferase; ALT – alanine aminotransferase; γ-GT – γ-glutamyl transpeptidase; APRI – AST-to-platelet ratio index.
•
Median with interquartile range (25th/75th%); statistics was done by Mann-Whitney method.