Table 4.
Association between children's isoflavone intake (milligrams per week) and KD using soy nonconsumers as a reference, stratified by ethnicity
| Isoflavone intake/categoriesa |
Whites (n = 274) | Asians (n = 51) | ||||
|---|---|---|---|---|---|---|
| IQR | No. of cases/controls | ORs (95% CI) | IQR | No. of cases/controls | ORs (95% CI) | |
| Total isoflavones | ||||||
| Soy nonconsumers, 0 | 75/91 | 1.00 (reference) | 7/12 | 1.00 (reference) | ||
| Low consumers, ≤16.6 | 3.3–11.9 | 21/31 | 0.88 (0.46–1.70) | 4.2–8.3 | 3/2 | 4.09 (0.46–36.18) |
| High consumers, >16.6 | 25.9–75.8 | 30/26 | 1.61 (0.86–3.01) | 25.4–152.1 | 20/7 | 7.29 (1.73–30.75) |
| P trend | 0.21 | 0.007 | ||||
| Continuous, mg/wkb | 126/148 | 1.12 (0.97–1.30) | 30/21 | 1.55 (1.11–2.17) | ||
| Genistein | ||||||
| Soy nonconsumers, 0 | 75/91 | 1.00 (reference) | 7/12 | 1.00 (reference) | ||
| Low consumers, ≤6.5 | 1.6–4.9 | 19/30 | 0.83 (0.42–1.62) | 1.6–6.2 | 3/3 | 2.82 (0.38–21.12) |
| High consumers, >6.5 | 13.0–39.1 | 32/27 | 1.65 (0.89–3.05) | 13.0–77.7 | 20/6 | 8.33 (1.92–36.24) |
| P trend | 0.17 | 0.005 | ||||
| Continuous, mg/wkb | 126/148 | 1.16 (0.97–1.39) | 30/21 | 1.61 (1.10–2.37) | ||
All analyses performed on log-transformed values, adjusted for age and sex; soy nonconsumers, reference.
Abbreviation: IQR, interquartile range for corresponding category.
a
Soy nonconsumers, reference group; low consumers, total isoflavone intakes below the median; high consumers, total isoflavone intakes above the median represent total intakes above and below the median among soy consumers, respectively.
b
Because of smallnumbers of observations in some cells, an overall continuous model was also performed; continuous model includes soy nonconsumers.