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. 2016 Jun 24;40(9):1232–1242. doi: 10.1097/PAS.0000000000000659

FIGURE 1.

FIGURE 1

MetaMorph quantification of SM in liver biopsies before and after olipudase alfa treatment. This staining and quantification method identifies and measures only abnormal SM accumulation, which is part of the disease process. The normal value in a non-ASMD liver is 0. The “n” for number of blocks analyzed by MetaMorph at baseline and week 26, respectively, for each patient are as follows: Patient 1, n=2, n=0; patient 2, n=4, n=8; patient 3, n=8, n=9; patient 4, n=5, n=6; patient 5, n=7, n=7. *P<0.0001.