Table 1.

Serum cytokines, whole blood thiamin concentration and intestine adenine-triphosphate in control and septic animals

	Control	Sepsis
		Mild	Moderate	Severe
IL-1β (pg/mL)	5.5 ± 1.4	38.4 ± 2.9	47.2 ± 6.6	148.9 ± 24.7*
IL-6 (pg/mL)	11.8 ± 4.6	78.4 ± 15.8	143.8 ± 12.8†	465.1 ± 46.2*
Thiamin (µg/L)§	51.9 ± 1.1	52.5 ± 0.8	51.1 ± 1.3	50.6 ± 0.3
ATP (nmol/mg protein)	12.9 ± 1.4	10.9 ± 1.1	6.2 ± 0.4*‡	5.4 ± 0.4*

Values are mean ± SE; n = 6,

^§thiamin blood concentration n = 4.

IL-1β: *P < 0.001 severe sepsis compared with control, mild and moderate sepsis.

IL-6: *P < 0.001 severe sepsis compared with control, mild and moderate sepsis;

^†P < 0.008 moderate sepsis compared with control.

Adenosine tri-phosphate (ATP):

^*P < 0.001 severe and moderate sepsis compared with control.

^*P = 0.003 severe compared with mild sepsis.

^‡P = 0.01 moderate compared with mild sepsis.