Table 1.
Clinical Covariates for miR-196b and miR-34c-5p Methylation Analysis in Sputum
| Covariates | Cases (N=82) | Controls (N=162) | p-Value1 |
|---|---|---|---|
| Sex | N (%) | N (%) | 0.71 |
| Male | 63 (77) | 121 (75) | |
| Female | 19 (23) | 41 (25) | |
| Age (Years) | 0.91 | ||
| Mean ± SD | 65 ± 7.6 | 65 ± 7.3 | |
| Range | 45, 80 | 46, 76 | |
| Race2 | N (%) | N (%) | 0.66 |
| Non-Hispanic White | 57 (70) | 117 (72) | |
| Hispanic | 20 (24) | 40 (25) | |
| Other | 5 (6) | 5 (3) | |
| Smoking Status | N (%) | N (%) | 0.80 |
| Current | 27 (33) | 56 (35) | |
| Former | 55 (67) | 106 (65) | |
| Pack Years | 0.27 | ||
| Mean ± SD | 56 ± 30.6 | 52 ± 26.5 | |
| Lung Cancer Stage | N (%) | ||
| I | 49 (60) | ||
| II | 11 (13) | ||
| III | 22 (27) | ||
| Histology | N (%) | ||
| Squamous Cell | 30 (36) | ||
| Adenocarcinoma | 40 (49) | ||
| NSCLC | 8 (10) | ||
| Other | 4 (5) |
1
Differences in covariates between cases and controls were assessed using Chi-square for categorical variables and Wilcoxon rank-sum test for continuous variables.
2
Race was dichotomized to non-Hispanic white and other.