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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2016 Feb 16;174(1):93–112. doi: 10.1002/ajmg.b.32429

FIG. 2.

FIG. 2

Schematic illustration of adult neurogenesis related pathways: there are five crucial modulators controlling neural stem cell (NSC) proliferation, differentiation, migration, and maintenance during adult neurogenesis: signaling transduction pathways, the vascular and immune systems, metabolic factors, and epigenetic regulation. These five modulators are composed of diverse molecules and biological pathways and mechanisms acting to control neurogenesis.