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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Gut. 2016 Feb 16;66(7):1197–1207. doi: 10.1136/gutjnl-2015-310341

Figure 1. AV content is increased in a food allergy-induced murine model of EoE-like oesophageal inflammation.

Figure 1

BALB/c mice were treated with MC903 and OVA for 18 days (n=3) or untreated as controls (n=4). (A) Oesophageal tissues were evaluated by H&E staining (arrows, eosinophils) and IHC for p63 (basal cells) and cleaved LC3 (autophagy). Scale bars, 50 µm. (B and C) Eos and p63-positive basal cells were determined. Oesophageal epithelial sheets were peeled in (D and E). (D) Immunoblot determined LC3-II (densitometry shown at bottom) with β-actin as a loading control. (E) Flow cytometry determined the Cyto-ID-positive fraction with representative histogram plot (Left) and average (Right) displayed for each condition. *p<0.05 vs. MC903/OVA (−).