Table 3. Neonatal data for infants born from multiple gestation after previable PPROM (n = 30, 2000–2015).
| Received antibiotics n = 17 (%) |
No antibiotics n = 13 (%) |
p Value | |
|---|---|---|---|
| Median latency A, wk, (IQR) | 0.8 (0.6, 2) | 2.4 (0.5, 4.6) | 0.21 |
| Median latency B, wk, (IQR) | 1.2 (0.6, 4.3) | 2.9 (0.9, 6.6) | 0.25 |
| Perinatal mortality (A) | 13 (76.5) | 10 (76.9) | > 0.99 |
| Perinatal mortality (B) | 11 (64.7) | 10 (76.9) | 0.38 |
| Median delivery gestational age A, (IQR) | 22.7 (18.8, 23.6) | 23 (21.9, 23.4) | 0.65 |
| Median delivery gestational age B, (IQR) | 23.0 (20.4, 23.7) | 23.6 (22.6, 25.0) | 0.44 |
| Maternal morbiditya | 7 (41.2) | 6 (46.2) | > 0.99 |
| Neonatal morbidityb (A) | 2/4 | 1/3 | > 0.99 |
| Neonatal morbidityb (B) | 1/6 | 1/3 | > 0.99 |
| Median delivery interval, wk, A to B, (IQR) | 0 (0, 0.2) | 0.1 (0, 0.4) | 0.21 |
Abbreviations: IQR, interquartile range; PPROM, preterm premature rupture of membranes.
a
Includes: Intensive care unit admission, sepsis, acute renal injury, blood transfusion, endometritis, hysterectomy, deep vein thrombosis, pulmonary embolism, and readmission.
b
Infants who were born at 23 wk or above and survived were included, includes: necrotizing enterocolitis, grade 3 or 4 intraventricular hemorrhage, bronchopulmonary dysplasia, pulmonary hypoplasia, and sepsis.