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. 2016 Aug 15;214(4):371–373. doi: 10.1083/jcb.201607118

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© 2016 O'Connor-Giles

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 1. — Motoneuronal regulation of microtubule dynamics. A newly identified Toll-6–FoxO signaling pathway negatively regulates Pav-KLP (Pav) levels at the Drosophila NMJ. Repression of Pav, a negative regulator of microtubule sliding, is required for axonal trafficking of synaptic components and activity-dependent addition of new boutons. Modified from McLaughlin et al. (2016).