Table 11.
Selected findings from Swaab laboratory on postmortem brain specimen of male-to-female transsexuals
| Structure and stained cells | Normative pattern of sexual dimorphism | MtFs | References | |
|---|---|---|---|---|
| Volume | Neurons number | |||
| BSTC | ||||
| VIP | M > F | Feminine | Zhou et al. (1995) | |
| Somatostatin | M > F | Feminine | Feminine | Kruijver et al. (2000) |
| INAH-1 | ||||
| Thionin | M > F | Masculine | Masculine | |
| Galanin | M > F | Masculine | Masculine | |
| VIP | M > F | Masculine | Masculine | |
| INAH-3 | M > F | Feminine | Feminine | García-Falgueras and Swab (2008) |
| Thionin | M > F | Isomorphic | Isomorphic | |
| NPY | M = F | Isomorphic | Isomorphic | |
| INAH-4 | M = F | |||
| Uncinate (ANAH-3 + ANAH-4) | ||||
| NPY | M = F | Isomorphic | Isomorphic | |
| Synaptophysin | M = F | Isomorphic | Isomorphic | |
| Infundibular nucleus | F > M | Feminine | Feminine | Taziaux et al. (2012) |
| NKB | F > M | Feminine | Feminine | |
| Kisspeptin | F > M | Feminine | Taziaux et al. (2016) | |
| Paraventricular nucleus | M = F | Isomorphic | Isomorphic | Zhou et al. (1995) |
| Suprachiasmatic nucleus | M = F | Isomorphic | Isomorphic | |
BSTC central region of the bed nucleus of stria terminalis, INAH interstitial nucleus of anterior hypothalamus (1, 3, 4), VIP vasointestinal peptide, NPY neuropeptide Y, NKB neurokinin B. Except for thionin staining, under each structure is indicated the type of cells marked using immunocytochemical techniques