Table 2.
Levels and prevalence of anti-IgG responses against tested antigens.
| Parameters | Cerebral malaria (n = 69) | Mild malaria (n = 72) | p | |
|---|---|---|---|---|
| IgG anti-PfSchz | N (%) | 35 (50) | 50 (69) | 0.021 |
| ODrt ± SE∗ | 3.80 ± 0.29 | 3.06 ± 0.42 | 0.063 | |
|
| ||||
| IgG anti-iRBCm | N (%) | 35 (50) | 63 (88) | <0.01 |
| ODrt ± SE | 2.75 ± 0.23 | 3.87 ± 0.39 | 0.032 | |
|
| ||||
| IgG anti-PfEB200 | N (%) | 15 (22) | 19 (26) | 0.518 |
| ODrt ± SE | 1.38 ± 0.14 | 1.21 ± 0.36 | 0.235 | |
|
| ||||
| IgG anti-R23 | N (%) | 10 (14) | 16 (22) | 0.236 |
| ODrt ± SE | 2.27 ± 0.33 | 1.98 ± 0.31 | 0.452 | |
|
| ||||
| IgG anti-PfEMP3/5 | N (%) | 37 (54) | 30 (42) | 0.155 |
| ODrt ± SE | 2.59 ± 0.54 | 3.82 ± 0.38 | 0.031 | |
∗IgG responses in OD ratio ± standard error.
N = number of positive responders that is individuals with OD ratio ≥2, (%) = prevalence of positive responses, ODrt = Mean Optical Densities ratio, SE = standard error, p = p value resulting from comparison with Mann-Whitney rank or Chi2 tests employed, respectively, for ODrt and prevalences of responders.