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. 2016 Aug;26(8):722–734. doi: 10.1016/j.numecd.2016.01.003

Table 2.

Hazard Ratios for incident heart failure outcome in 20,922 men and women of the EPIC-Norfolk cohort by chocolate consumption.

Quintiles of daily chocolate intake Quintile 1
0 g/day (n = 4236)
Quintile 2
0.6–3.4 g/day (n = 3521)
Quintile 3
3.5–6.9 g/day (n = 4386)
Quintile 4
7.0–15.5 g/day (n = 4582)
Quintile 5
15.6–98.8 g/day (n = 4198)
p-value for trend across median chocolate intake in each group
Model 1 1.00 (ref) 0.83 (0.69–0.99) 0.87 (0.73–1.03) 0.78 (0.66–0.93) 0.75 (0.62–0.91) 0.013
Model 2 1.00 (ref) 0.93 (0.78–1.11) 0.97 (0.81–1.16) 0.89 (0.74–1.06) 0.87 (0.71–1.06) 0.193
Model 3 1.00 (ref) 0.92 (0.77–1.11) 0.96 (0.80–1.15) 0.89 (0.74–1.06) 0.87 (0.71–1.06) 0.194

Model 1: Age, sex adjusted.

Model 2: Age, sex, education, body mass index (per unit), social class, physical activity, smoking status, dietary energy (per kJ/day), alcohol consumption (per g/day), myocardial infarction, diabetes, arrhythmia adjusted.

Model 3: Age, sex, education, body mass index (per unit), social class, physical activity, smoking status, dietary energy (per kJ/day), alcohol consumption (per g/day), myocardial infarction, diabetes, arrhythmia, systolic blood pressure (per mmHg), cholesterol level (per mmol/L), heart rate (per beat) adjusted.