Change in risk factors by weight loss group and gender, among patients with elevated baseline risk factors. Asterisk indicates that after adjusting for effects of baseline risk factor values, baseline BMI, gender, and age, losing >10 % decreased risk factor values significantly more than losing 5–10 and <5 %, with no other differences (p < .05). Dagger indicates that after adjusting for effects of baseline HDL value, baseline BMI, gender, and age, there was a significant time by sex interaction (p < .05)