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. 2016 Aug 17;6:31593. doi: 10.1038/srep31593

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) The fluorescence of Cy5.5-Lira in ICR mice was monitored by non-invasive live imaging at different time points after SC injection. (b) Ex vivo organ distributions of degradation segments of Cy5.5-Lira at indicated days after SC injection. The livers, kidneys, lungs, spleens and hearts were isolated from mice at predetermined time points and fluorescence intensities were monitored. “D” denotes “day”.