Table 6. Inhibitory effects of some compounds from T. chinensis on NO production induced by LPS in macrophagesac.
Compound | IC50 (μM)a | Compound | IC50 (μM)a |
---|---|---|---|
1 | 28.7 ± 2.1 | 15 | 46.1 ± 13.1 |
4 | 21.7 ± 1.3 | 17 | 21.0 ± 0.8 |
5 | 45.9 ± 3.1 | 18 | 41.6 ± 13.5 |
7 | 45.2 ± 5.7 | 19 | 45.4 ± 11.2 |
9 | 33.6 ± 1.7 | 20 | 22.6 ± 5.0 |
10 | 28.7 ± 4.5 | 21 | 11.5 ± 1.3 |
13 | 26.1 ± 0.5 | Indomethacinb | 47.4 ± 4.5 |
14 | 29.1 ± 0.6 |
aValues are presented as means ± SD (n = 3).
bPositive control.
cCompounds 2, 3, 6, 8, 11, 12, 16, 19, 22, 23 with IC50 > 50.0 μM.