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. Author manuscript; available in PMC: 2016 Aug 17.
Published in final edited form as: Toxicol Sci. 2016 Apr 21;152(1):85–98. doi: 10.1093/toxsci/kfw074

FIG. 1.

FIG. 1

Confirmation of sensitization and evaluation of skin irritancy following dermal TDI exposure. ELISA analysis of total serum IgE levels 11 days following single TDI exposure at the indicated concentration (A). Percent change in ear thickness as determined 4 days following TDI exposure (B). Ear mRNA expression of the inflammatory cytokines il-1β (C), il-6 (D), and tnf-α (E) as determined 4 days following TDI exposure via RT-PCR. Bars represent mean (± SE) of 4–5 mice per group. Statistical significance is indicated by (*) at a P-value < .05 and (**) at a P-value < .01.