Table 1.

Spearman rank order correlations related to the operated limb at experimental end-point between various biologically relevant clinical and end-point measures (p < 0.05), at either 0 or 20 weeks, or the difference in operated limb over time, or between operated and control hind limb

Clinical factor	Clinical or end-point factor	ρ
Change in bodyweight 0–20 weeks	Operated total joint & femoral head Mankin score	−0.82– −0.79
Change in bodyweight 0–20 weeks	Range of motion operated limb at 20 weeks	0.89
Range of motion operated limb at 20 weeks	Operated total joint and femoral head Mankin score	−0.96– −0.93
Range of motion operated limb at 20 weeks	Maximum peak pressure, force and impulse O:C at 20 weeks	0.82–0.89
Range of motion operated limb at 20 weeks	Impulse O:C 20 weeks	0.82
Difference in range of motion between operated and control 20 weeks	Operated acetabulum Mankin score	−0.93
Difference in range of motion between operated and control 20 weeks	Bodyweight distribution to operated limb at 20 weeks	0.89
Limb circumference operated limb	Operated mean synovial score	−0.86
Limb circumference operated limb	Control mean synovial score	0.79
CBPI 20 weeks	Bodyweight distribution change hind limbs 0–20 weeks	−0.77
CBPI 20 weeks	Bodyweight distribution change forelimbs 0–20 weeks	0.77
CBPI 20 weeks	Bodyweight distribution to operated limb at 20 weeks	−0.85
Bodyweight distribution to operated limb at 20 weeks	Operated acetabulum Mankin score	−0.82
Bodyweight distribution change operated 0–20 weeks	Operated mean synovial score	−0.93
Bodyweight distribution to operated limb at 20 weeks	Control limb acetabulum Mankin score zone 2,6	0.79–0.90
Bodyweight distribution to operated limb at 20 weeks	Bodyweight distribution to operated limb at 0 weeks	0.86
Bodyweight distribution change operated 0–20 weeks	Impulse O:C at 20 weeks	0.79
Maximum force O:C 20 weeks	Operated total joint and femoral head Mankin score	−0.86– −0.79
Maximum force O:C 20 weeks	Control femoral head Mankin score	−0.83
Maximum force O:C 20 weeks	Impulse O:C 20 weeks	0.96
Maximum peak pressure O:C 20 weeks	Operated total joint and femoral head Mankin score	−0.96– −0.93
Radiographic score operated 20 weeks	Operated mean synovial and total joint Mankin score	0.77–0.79
Compression index operated 20 weeks	Operated mean synovial score	0.82
Compression index operated 20 weeks	Distraction index operated 20 weeks	0.86
Compression index operated 20 weeks	Radiographic score operated 20 weeks	0.77
Compression index operated 20 weeks	Mean number night activity bouts 20 weeks	−0.79
Distraction index operated 20 weeks	Radiographic score operated 0 weeks	0.94

Notes: CBPI canine brief pain inventory, O:C operated vs. control