Fig. 4.
The full and empty RV-C15a particle structures differ in regions at the capsid interior. The VP1 N terminus and VP4 undergo structural rearrangements when the empty particle (A) and full particle (B) structures are compared. Amino acid residues are shown as CĪ± backbones. VP4, VP2, and VP1 are colored orange, green, and blue, respectively. In the RV-C15a full particle structure, His1030, together with a conserved residue Trp2038 shared by many EV, are involved in forming an RNA binding site.