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. 2016 Jul 22;113(32):9015–9020. doi: 10.1073/pnas.1603883113

Fig. S1.

Fig. S1.

Toxicity of MAL3-101 and four MAL3-101 stereoisomers in RMS13 rhabdomyosarcoma cells. Stereoisomers were prepared as described in the SI Methods. Cells were incubated with either stereoisomers or MAL3-101 at the indicated concentrations for 72 h and viability was assayed with CellTiter-Glo. Data represent the means of three independent experiments ± SD. Stereoisomer 1 (Fraction 1): tR 23.3 min; Stereoisomer 2 (Fraction 2): tR 25.3 min; Stereoisomer 3 (Fraction 3): tR 29.3 min; Stereoisomer 4 (Fraction 4): tR 32.0 min (ChiralPak IA); Stereoisomers 1 and 4 as well as Stereoisomers 2 and 3 are enantiomeric pairs.