Table S2.
Top regulators of transcriptional networks after MAL3-101 treatment as predicted by Ingenuity Pathway Analysis
| Regulator | Description | Activation z-score | P value |
| EIF2AK3 | PERK | 3.501 | 3.51E-04 |
| Valproic acid | Antiepileptic medication | 5.697 | 7.24E-04 |
| PKCs | Protein kinase C signaling | 2.356 | 1.11E-03 |
| Lactacystin | Protease inhibitor | 2.432 | 2.82E-03 |
| miR-291a-3p | Mature microRNA with seed AAGUGCU | −4.563 | 3.32E-03 |
| Lipopolysaccharide | Bacterial cell wall component | 5.277 | 3.89E-03 |
| XBP1 | Effector of IRE1 signaling | 6.754 | 5.29E-03 |
| ATF4 | Effector of PERK signaling | 6.065 | 7.89E-03 |
| miR-181a-5p | Mature microRNA with seed ACAUUCA | −7.936 | 9.96E-03 |
| A23187 | Divalent cation binder | 3.796 | 1.02E-02 |