Fig. S7.

Comparison of mechanical response between point-like and finite-sized CMs. We perform finite-element simulations in COMSOL. We embed 36 elastic inclusions (CMs) within a surrounding elastic matrix, as shown in A. We impose a contractile eigenstrain in one of the centrally located CMs. We plot (B) the maximum strain induced in the neighboring centrally located CM against our analytic result for point-like CMs as a function of effective tissue Young’s modulus. We observe good quantitative agreement between the two models, justifying our approximation of CMs as point-like elastic inclusions.