Table 2. Spearman's rho (ρ) Coefficients in Both Groups of Differentially Correlated Transcripts Involved in the Identified Pathways (Table 2A: Cytokine–Cytokine Receptor Interaction, Table 2B: Neuroactive Ligand Receptor Interaction).
Transcript | ρ CG | ρ EA |
---|---|---|
Table 2A: KEGG cytokine–cytokine receptor interactions | ||
IL6ST | 0.53 | −0.57 |
CCL18 | 0.52 | −0.35 |
CXCR4 | 0.46 | 0.69 |
CCL11 | 0.45 | 0.06 |
IL21 | 0.43 | −0.15 |
OSMR | 0.39 | 0.03 |
CCL7 | 0.38 | −0.23 |
TNFRSF1A | 0.37 | −0.3 |
LEP | 0.37 | −0.13 |
IL1R2 | 0.37 | 0.02 |
IL18RAP | 0.36 | 0.18 |
TNFRSF19 | 0.17 | −0.39 |
TNFRSF6 | 0.11 | 0.42 |
TNFRSF14 | −0.4 | −0.35 |
CXCR3 | −0.41 | 0.43 |
ACVR2B | −0.42 | −0.15 |
CX3CR1 | −0.43 | −0.25 |
PRLR | −0.43 | −0.22 |
TNFRSF25 | −0.43 | 0.18 |
CXCL10 | −0.43 | 0.24 |
CCL8 | −0.46 | 0.02 |
FLT1 | −0.47 | −0.07 |
CCL2 | −0.7 | 0.17 |
Table 2B: KEGG neuroactive ligand receptor interaction | ||
ADORA3 | 0.68 | 0.4 |
LTB4R | 0.54 | −0.07 |
P2RY1 | 0.53 | −0.05 |
GHRHR | 0.47 | 0.08 |
GRID1 | 0.44 | 0.01 |
GRIA4 | 0.39 | 0.38 |
LEP | 0.37 | −0.13 |
HTR2B | 0.12 | −0.42 |
P2RX7 | 0.07 | −0.54 |
ADORA2A | 0.02 | −0.48 |
TSHB | −0.02 | 0.56 |
PTGDR | −0.12 | 0.58 |
GRIK3 | −0.13 | 0.35 |
SSTR5 | −0.27 | 0.42 |
MC2R | −0.31 | 0.55 |
GHSR | −0.31 | 0.59 |
CALCRL | −0.34 | 0.05 |
GRM1 | −0.37 | 0.11 |
P2RY6 | −0.4 | 0.14 |
GABRE | −0.4 | 0.08 |
GLP2R | −0.4 | 0.14 |
HRH1 | −0.42 | 0.01 |
PRLR | −0.43 | −0.22 |
PTGFR | −0.45 | −0.05 |
GRIN2A | −0.45 | −0.09 |
ADRB3 | −0.47 | 0.11 |
GRIK2 | −0.49 | 0.06 |
TRHR | −0.6 | 0.06 |
AVPR2 | −0.63 | 0.08 |
The mean difference between correlation coefficients was 0.49 in the cytokine–cytokine receptor interaction pathway and 0.52 in the neuroactive ligand receptor interaction pathway