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. 2016 May 11;41(10):2530–2540. doi: 10.1038/npp.2016.57

Table 2. Spearman's rho (ρ) Coefficients in Both Groups of Differentially Correlated Transcripts Involved in the Identified Pathways (Table 2A: Cytokine–Cytokine Receptor Interaction, Table 2B: Neuroactive Ligand Receptor Interaction).

Transcript ρ CG ρ EA
Table 2A: KEGG cytokine–cytokine receptor interactions
 IL6ST 0.53 −0.57
 CCL18 0.52 −0.35
 CXCR4 0.46 0.69
 CCL11 0.45 0.06
 IL21 0.43 −0.15
 OSMR 0.39 0.03
 CCL7 0.38 −0.23
 TNFRSF1A 0.37 −0.3
 LEP 0.37 −0.13
 IL1R2 0.37 0.02
 IL18RAP 0.36 0.18
 TNFRSF19 0.17 −0.39
 TNFRSF6 0.11 0.42
 TNFRSF14 −0.4 −0.35
 CXCR3 −0.41 0.43
 ACVR2B −0.42 −0.15
 CX3CR1 −0.43 −0.25
 PRLR −0.43 −0.22
 TNFRSF25 −0.43 0.18
 CXCL10 −0.43 0.24
 CCL8 −0.46 0.02
 FLT1 −0.47 −0.07
 CCL2 −0.7 0.17
     
     
Table 2B: KEGG neuroactive ligand receptor interaction
 ADORA3 0.68 0.4
 LTB4R 0.54 −0.07
 P2RY1 0.53 −0.05
 GHRHR 0.47 0.08
 GRID1 0.44 0.01
 GRIA4 0.39 0.38
 LEP 0.37 −0.13
 HTR2B 0.12 −0.42
 P2RX7 0.07 −0.54
 ADORA2A 0.02 −0.48
 TSHB −0.02 0.56
 PTGDR −0.12 0.58
 GRIK3 −0.13 0.35
 SSTR5 −0.27 0.42
 MC2R −0.31 0.55
 GHSR −0.31 0.59
 CALCRL −0.34 0.05
 GRM1 −0.37 0.11
 P2RY6 −0.4 0.14
 GABRE −0.4 0.08
 GLP2R −0.4 0.14
 HRH1 −0.42 0.01
 PRLR −0.43 −0.22
 PTGFR −0.45 −0.05
 GRIN2A −0.45 −0.09
 ADRB3 −0.47 0.11
 GRIK2 −0.49 0.06
 TRHR −0.6 0.06
 AVPR2 −0.63 0.08

The mean difference between correlation coefficients was 0.49 in the cytokine–cytokine receptor interaction pathway and 0.52 in the neuroactive ligand receptor interaction pathway