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Flowchart and outputs of SynBuilder. (A) Given options (a reference species, target species, and optional outgroup species, and a resolution) selected by users, SynBuilder creates synteny blocks using pairwise whole-genome alignments between the reference and the other species. (B) The output of SynBuilder (white box, coordinates of synteny blocks; below, the Circos plot) for four species (human, chimpanzee, gorilla and mouse) with three outgroup species (cat, dog and chicken).
