Table 2. Tools used more than five times a day on average: usage in 2008 and 2015.
| Tool | 2008 | 2015 |
|---|---|---|
| Ali2D | 136 | 2620 |
| AlignmentViewer | 339 | 4997 |
| BLASTClust | 980 | 6531 |
| Clustal Omega | 575 | 3416 |
| CS-BLAST | 67 | 2063 |
| HHalign | 205 | 1906 |
| HHblits | – | 4353 |
| HHpred | 12562 | 328973 |
| MAFFT | 203 | 3637 |
| MARCOIL | – | 4289 |
| Modeller | 2401 | 20134 |
| MUSCLE | 414 | 2706 |
| PCOILS | 584 | 5542 |
| ProbCons | 245 | 2343 |
| PSI-BLAST | 1302 | 3049 |
| Quick2D | 811 | 5783 |
| 6FrameTranslation | 328 | 5298 |
| TPRpred | 364 | 4350 |
| Total (all 53 tools) | 25 611 | 430 296 |
Tools developed in our group are shown in boldface and tools added since our last publication on the Toolkit in 2006 are underlined.