Table 2.
Top disease and function altered as response to ZEA exposure
| ID | Top diseases and functions | Score | Focus molecules |
|---|---|---|---|
| 1 | Cell Morphology, Cellular Assembly and Organization, Cellular Function and Maintenance | 40 | 34 |
| 2 | Metabolic Disease, Neurological Disease, Organismal Injury and Abnormalities | 38 | 33 |
| 3 | Auditory Disease, Hereditary Disorder, Neurological Disease | 38 | 33 |
| 4 | Molecular Transport, Hereditary Disorder, Connective Tissue Disorders | 35 | 32 |
| 5 | Digestive System Development and Function, Endocrine System Development and Function, Organ Morphology | 31 | 30 |
| 6 | Cellular Movement, Cell-To-Cell Signalling and Interaction, Nervous System Development and Function | 31 | 30 |
| 7 | Cancer, Cell Death and Survival, Organismal Injury and Abnormalities | 31 | 30 |
| 8 | Gene Expression, Protein Synthesis, RNA Post-Transcriptional Modification | 29 | 29 |
| 9 | Cell Death and Survival, Cell Morphology, Infectious Disease | 29 | 29 |
| 10 | Cardiovascular System Development and Function, Cancer, Cardiovascular Disease | 29 | 29 |
| 11 | Connective Tissue Disorders, Immunological Disease, Inflammatory Disease | 28 | 28 |
| 12 | Tissue Development, Post-Translational Modification, Cell Cycle | 28 | 28 |
| 13 | Cell Cycle, DNA Replication, Recombination, and Repair, Cellular Compromise | 26 | 27 |
| 14 | Nucleic Acid Metabolism, Small Molecule Biochemistry, Cell Cycle | 26 | 27 |
| 15 | DNA Replication, Recombination, and Repair, Cell Cycle, Reproductive System Development and Function | 26 | 27 |
| 16 | Cellular Growth and Proliferation, Embryonic Development, Organ Development | 26 | 27 |
| 17 | RNA Post-Transcriptional Modification, Developmental Disorder, Hereditary Disorder | 26 | 27 |
| 18 | Developmental Disorder, Hereditary Disorder, Skeletal and Muscular Disorders | 26 | 27 |
| 19 | Protein Synthesis, Cancer, Organismal Injury and Abnormalities | 26 | 27 |
| 20 | Energy Production, Lipid Metabolism, Small Molecule Biochemistry | 26 | 27 |
| 21 | Cellular Assembly and Organization, Inflammatory Disease, Inflammatory Response | 24 | 26 |
| 22 | Lipid Metabolism, Molecular Transport, Small Molecule Biochemistry | 24 | 26 |
| 23 | RNA Post-Transcriptional Modification, Carbohydrate Metabolism, Cellular Compromise | 24 | 26 |
| 24 | Amino Acid Metabolism, Small Molecule Biochemistry, Cell Signaling | 24 | 26 |
| 25 | Infectious Disease, Organismal Injury and Abnormalities, Dermatological Diseases and Conditions | 24 | 26 |