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. 2016 Aug 17;15:48. doi: 10.1186/s12941-016-0164-y

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Combination of AgNPs, blue light, and clarithromycin against two isolates of MRSA. The triple combination of AgNPs with the blue light and clarithromycin against two isolates of MRSA was assessed. The isolates were selected on the basis of synergistic response in checkerboard assay. Based on the best result of the combination in the checkerboard assay, the concentrations of the two agents were used as follow: a Isolate C51: AgNPs at 1/8 of the MIC, and azithromycin at 0.25 µg/mL. b Isolate C41: AgNPs at 1/512 of the MIC, and azithromycin at 0.25 µg/mL. AgNPs silver nanoparticles, CFU colony forming unit, CLR clarithromycin, SD standard deviation