Fig. 1.

miR-15b expression is up-regulated in uterine leiomyoma tissue and cultured cells. a Comparison of miR-15b expression level between isolated pLYO tissue and paired pMYO tissue. b Expression level of miR-15b in cpLYO cells as well as cpMYO cells. c Comparison of miR-15b level between pLYO cells and pMYO cells. Quantitative RT-PCR assay was performed as described in the methods section. All data were presented as mean ± SD and analyzed using Student’s t-test (two tail, unequal variance) and Mann–Whitney U test applicable. The experiments were performed in triplicate. Statistical significance was noted as * p < 0.05, ** p < 0.005, *** p < 0.001