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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Am J Surg Pathol. 2016 Sep;40(9):1192–1202. doi: 10.1097/PAS.0000000000000662

Figure 1. Typical Morphologic Features of Pancreatic WD-NET, PD-NEC-SCC, and PD-NEC-LCC.

Figure 1

WD-NETs (A-B) revealed nested/organoid and trabecular architecture, a regular intratumoral vascular pattern, abundant granular cytoplasm, and stippled nuclei with inconspicuous nucleoli. PD-NEC-SCC (C-D) demonstrated stromal desmoplasia (C), tumor necrosis (C), fusiform (“oat cell”) nuclei lacking nucleoli, and nuclear molding. PD-NEC-LCC (E-F) displayed tumor necrosis, expansile and irregular nests with peripheral palisading, and rosettes/tubular structures within the large nests.