FIG 7.

Promotion of CD4bs antibody association with trimeric Env by CD4i antibodies and CCR5mim2-Ig. (A) Experiment similar to that for Fig. 6 except that cells were preincubated with E51 at serially diluted concentrations starting at 50 μg/ml. Cells were washed and then incubated with 0.01 μg/ml of the indicated CD4bs antibody or CD4-Ig. Analysis was performed as for Fig. 4 except that MFI data were normalized to the value of each antibody or CD4-Ig binding without E51 preincubation. (B) Experiment similar to that for panel A except that cells were preincubated with 50 μg/ml of 412d, 17b, or CCR5mim2-Ig. Note that the scale of the y axes varies between graphs. Error bars represent SEM.