FIG 7.

Impact of viral proteins on the antiviral function of NF-κB. Plasmids encoding the indicated SC35M segments were combined with plasmids encoding the other SC35 segments to produce reassortant viruses. These chimeric viruses and the SC35 and SC35M controls were then used to infect control MLE-15 cells, MLE-15 NEMO⁻ cells, or MLE-15 p65⁻ cells (MOI of 0.001), and virus titers were determined 24 h p.i. Mean values from three independent experiments are shown. Error bars indicate SEM. The P values are indicated by asterisks: *, P < 0.05; **, P < 0.01; ***, P < 0.001.