Table 1.
Infectivity (ID50) of the different G serotypes of human rotavirus inoculum for mini-pigs (3-5 d old)
| Virus shedding1 | Diarrhea3 | ||||||||
| Inoculum RV serotype (G) | Animal species | Animal number | Percentage shedding | Mean onset (d) | Mean duration (d) | Peak titer shed (FFUs/mL) | Percentage with diarrhea | Mean onset (d) | Mean cumulative faecal score |
| Wa (attenuate) | Guizhou | 3 | 33%2 | 2 | 2 | 1 × 103 | 0 | 0 | 4 |
| Bamma | 3 | 33%2 | 2 | 1 | 5 × 102 | 0 | 0 | 6 | |
| G1 | Guizhou | 3 | 100% | 1 | 6 | 2 × 106 | 100% (3/3) | 1.2 | 14 |
| Bamma | 3 | 100% | 1 | 6 | 1 × 106 | 100% (3/3) | 1 | 12 | |
| G3 | Guizhou | 3 | 100% | 1 | 7 | 2 × 107 | 100% (3/3) | 1.5 | 16 |
| Bamma | 3 | 100% | 1 | 7 | 5 × 106 | 100% (3/3) | 1 | 12 | |
| PBS | Guizhou | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Bamma | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
1
Determined by FFA assay;
2
The virus shedding animal is randomly selected;
3
Diarrhea present if daily fecal consistency score ≥ 2, mean cumulative fecal score = ∑ (Daily fecal scores from 1-7 DPI)/n. FFUs: Focus forming units; DPI: Days post infection.