5-FU |
miR-21 |
Overexpression |
Pancreatic cancer |
Donahue et al[126], J Surg Oncol 2014 |
5-FU and irinotecan |
pri-miR26a-1 |
rs7372209 polymorphism |
Colorectal cancer |
Boni et al[132], Pharmacogenomics J 2011 |
5-FU and oxaliplatin |
miR-106a, miR-484, miR-130b |
Overexpression |
Colorectal cancer |
Kjersem et al[143], Mol Oncol 2014 |
5-FU, paclitaxel and oxaliplatin |
miR-27a |
Overexpression |
Gastric cancer |
Huang et al[135], J Cell Biochem 2014 |
5-FU, capecitabine and oxaliplatin |
miR-625-3p, miR-181b, miR-27b |
Overexpression |
Colorectal cancer |
Rasmussen et al[133], Mol Oncol 2013 |
Irinotecan and cetuximab |
miR-345 |
Overexpression |
Colorectal cancer |
Schou et al[144], PLoS One 2014 |
Oxaliplatin |
miR-203 |
Overexpression |
Colorectal cancer |
Zhou et al[145], Mol Oncol 2014 |
Carboplatin and paclitaxel ± sorafenib |
miR-659-3p |
Downregulation |
Melanoma |
Villaruz et al[136], Clin Epigenetics 2015 |
Paclitaxel |
miR-200c |
Downregulation |
Ovarian and endometrial cancer |
Cochrane et al[146], Mol Cancer Ther 2009 |
Paclitaxel |
miR-145 |
Downregulation |
Ovarian cancer |
Zhu et al[147], Int J Cancer 2014 |
Paclitaxel |
miR-17-5p |
Downregulation |
Lung cancer |
Aggarwal et al[148], Planta Med 2008 |
Gemcitabine |
miR-21 |
Overexpression |
Pancreatic cancer |
Hwang et al[127], PLoS One 2010 |
Giovannetti et al[128], Cancer Res 2010 |
Caponi et al[129], Ann Oncol 2013 |
Gemcitabine |
miR-21, miR-23a, miR-27a |
Overexpression |
Pancreatic cancer |
Frampton et al[131], Gastroenterology 2014 |