Table 3.
Enantiomeric ratios (ERs) of synthetic cathinones present in the samples of “legal highs”
| Compound | Chromatographic conditions | Area % E1 | Area % E2 | ER |
|---|---|---|---|---|
| Blast A2 (flephedrone) | A | 50.08 ± 0.02 | 49.92 ± 0.02 | 1.00 |
| Standard pentedrone | A | 51.38 ± 0.02 | 48.62 ± 0.02 | 1.06 |
| Standard 4-MEC | A | 63.53 ± 0.01 | 36.47 ± 0.01 | 1.74 |
| Cyclop A5 (3,4-DMMC) | A | 50.02 ± 0.02 | 49.98 ± 0.02 | 1.00 |
| Bliss A7 (methedrone) | A | 47.35 ± 0.02 | 52.65 ± 0.02 | 0.90 |
| Kick A13 (buphedrone) | A | 50.27 ± 0.01 | 49.73 ± 0.01 | 1.01 |
| Standard methylone | A | 50.04 ± 0.03 | 49.96 ± 0.03 | 1.00 |
| Rush A3 (buphedrone) | A | 50.20 ± 0.02 | 49.80 ± 0.02 | 1.01 |
| Blow A11 (4-MEC) | A | 62.94 ± 0.02 | 37.06 ± 0.02 | 1.70 |
| Blow A10 (4-MEC) | A | 61.90 ± 0.01 | 38.10 ± 0.01 | 1.62 |
| Bliss A6 (methedrone) | A | 49.88 ± 0.03 | 50.12 ± 0.03 | 1.00 |
| Kick A12 (pentedrone) | A | 54.06 ± 0.02 | 45.94 ± 0.02 | 1.18 |
| Crabby A4 (3,4-DMMC) | A | 49.21 ± 0.02 | 50.79 ± 0.02 | 0.97 |
| Bloom A1 (ethcathinone) | A | 50.14 ± 0.01 | 49.86 ± 0.01 | 1.01 |
| Bloom A1 (pentedrone) | A | 50.20 ± 0.02 | 49.80 ± 0.02 | 1.01 |
| Bloom A1 (methedrone) | A | 49.76 ± 0.02 | 50.24 ± 0.02 | 0.99 |
| Bliss A14 (methylone) | A | 49.96 ± 0.02 | 50.04 ± 0.02 | 1.00 |
| Standard MDPV | B | 49.97 ± 0.02 | 50.03 ± 0.02 | 1.00 |
Condition A column: Chiralpak® AS-H, mobile phase Hex/2-PrOH/TEA (97:3:0.1,v/v/v), flow rate 0.5 mL/min, ultraviolet (UV) detection 254 nm
Condition B column: CSP1 coated onto APS-Nucleosil, mobile phase Hex/ethanol/TEA (97:3:0.1,v/v/v), flow 0.5 mL/min, UV detection 254 nm (n = 3)
E1, E2 peak area of each enantiomer