Table 3. Results of Crossover (Mixed-Effect Model) Analysis, Stratified by Visual Acuity at Baseline (Post hoc Analysis). Bevacizumab.
Baseline visual acuity letter score | Bevacizumab [95% CI] | Ranibizumab [95% CI] | Difference [95% CI] | P-Value | |
---|---|---|---|---|---|
Best-Corrected Visual Acuity, Change from Baseline (letters) | Any (all eyes) | 5.3 [3.2, 7.4] | 6.6 [4.5, 8.7] | 1.3 [0.07, 2.5] | 0.039 |
≥ 69 letters | 3.1 [0.2, 6.0] | 3.6 [0.7, 6.5] | 0.45 [−1.4, 2.3] | 0.64 | |
< 69 letters | 6.9 [4.3, 9.4] | 8.7 [6.2, 11.3] | 1.9 [0.3, 3.5] | 0.022 | |
OCT Central Subfield Mean Thickness, Change from Baseline (μm) | Any (all eyes) | −89 [−116, −62] | −137 [−164, −110] | −48 [−65, −31] | <0.001 |
≥ 69 letters | −106 [−144, −68] | −145 [−183, −108] | −40 [−66, −14] | 0.0032 | |
< 69 letters | −78 [−111, −45] | −132 [−165, −99] | −54 [−76, −31] | < 0.001 |