Table 2.
Correlations and mean estimates for hypothesized predictors of depression response after 16 weeks of depression treatment
| 1 Predictor |
2 Mean ± SD / N (%) |
3 Estimate (95% CI) | P |
|---|---|---|---|
|
| |||
| BDI-II score | |||
| Baseline | 30.2 ± 8.5 | 0.19 (0.03, 0.35) | 0.02 |
|
| |||
| Prior depressive episode | |||
| Yes | 122 (77.7%) | 8.3 ± 7.7 (6.9, 9.7) | 0.53 |
| No | 35 (22.3%) | 9.3 ± 8.1 (6.6, 12.0) | |
|
| |||
| BAI score | |||
| Baseline | 14.5 ± 8.9 | 0.04 (−0.13, 0.22) | 0.61 |
|
| |||
| Stressful life events | |||
|
| |||
| Stressful life events score (SLEQ) | |||
| Baseline (prior 12 months) | 8.9 ± 7.0 | 0.02 (−0.15, 0.20) | 0.81 |
| Treatment Weeks 1-8 | 4.3 ± 4.1 | 0.19 (0.02, 0.36) | 0.03 |
| Treatment Weeks 9-16 | 3.7 ± 4.0 | 0.40 (0.24, 0.55) | <0.0001 |
|
| |||
| Medical events during treatment | |||
| Hospitalization | 0.40 | ||
| Yes | 32 (20.4) | 7.3 ± 9.0 (4.1, 10.4) | |
| No | 125 (79.6) | 8.9 ± 8.0 (7.4, 10.3) | |
| Emergency department visit | 0.90 | ||
| Yes | 31 (19.7) | 8.7 ± 8.6 (5.7, 11.8) | |
| No | 126 (80.3) | 8.5 ± 8.2 (7.0, 9.9) | |
|
| |||
| Depression Treatment Adherence | |||
|
| |||
| Medication compliance (% of pills removed from container) |
97.0 ± 5.5 | −0.47 (−0.76, 0.05) | 0.08 |
|
| |||
| % CBT homework completed | 59.7± 26.8 | −0.29 (−0.44, −0.12) | 0.001 |
Depression scores at 16 weeks are regressed on the hypothesized predictor, controlling for age, baseline depression scores and baseline antidepressant use. Cardiac or other medical events occurring during treatment were also included in all models except SLEQ. BAI models were further adjusted for anxiolytic use at baseline.
Summary scores for the continuous predictor variables are reported as mean ± SD. Categorical variables are reported as the number and (%) of participants.
Estimates are presented as partial Fisher z-transformed Pearson correlations for continuous predictors and mean ± SD post treatment BDI-II scores for dichotomous predictors.