Table 1.

Linkage between miRNA and mTOR signaling pathway

Authors	Cell line(s)	Type of disease	Type of miRNA	Target*	Finding/Suggestion for miRNA
Zheng et al. (27)	SGC-7901 cell	Gastric cancer	miRNA-18a	Vacuolar protein sorting- associated protein 13D	Possible therapeutic strategy against malignancy
Wan et al. (28)	CNE and HeLa cells	Hypoxia- induced autophagy	miRNA-155	Kinesin-like protein KIF1B Nuclear factor 1 A-type	A key regulator of autophagy via dysregulation of mTOR pathway
Shen and Houghton (29)	CB17SC SCID mice	Childhood sarcoma	miRNA-18a	Vacuolar protein sorting- associated protein 13D	Oncogenic growth signals may promote tumorigenesis by dampening the ATM checkpoint
			miRNA-421	Calmodulin-binding transcription activator 1 Arginine-glutamic acid dipeptide repeats protein
Zhong et al. (30)	Colorectal carcinoma cell	Colorectal carcinoma	miRNA-30a	FUS-interacting serine- arginine-rich protein 1	A potential therapeutic target to block CRC metastasis
			miRNA-30b	Kinesin-like protein KIF1B MARCKS-related protein
Wang et al. (31)	Mouse adult pancreatic islets	Diabetes	miRNA-7	Kinesin-like protein KIF1B FKBP12-rapamycin complex-associated protein	As a therapeutic target for diabetes
Li et al. (32)	MG63 cells	Osteosarcoma	miRNA-223	AR DNA-binding protein 43 Msx2-interacting protein FUS-interacting serine- arginine-rich protein 1	Could be used in anticancer therapies in osteosarcoma
Cui et al. (33)	Renal cell Carcinoma cell	Renal cell carcinoma	miRNA-99a	Uncharacterized protein C1orf34 plasticity related gene 1	May offer an attractive new target for diagnostic and therapeutic interventions
Iwaya et al. (34)	HT29 and CaR-1 cell	Colorectal carcinoma	miRNA-144	PR domain zinc finger protein 2 Msx2-interacting protein	A meaningful prognostic marker
Gebeshuber and Martinez (35)	Breast cancer cell	Breast cancer	miRNA-100	TAR DNA-binding protein 43 Uncharacterized protein C1 or f34	A potential target for therapeutic approaches

*; Predicted by target scan and mTOR; Mammalian target of rapamycin.