Table 1. Characteristics of the study population.
Control group | Patients | P-value | |
---|---|---|---|
n = 10 | n = 26 | ||
Age (y) | 62 ± 11 | 68 ± 5 | 0.068 |
Gender (f/m) | 7 / 3 | 10 / 16 | - |
Height (cm) | 170 ± 8 | 170 ± 8 | 0.771 |
Weight (kg) | 68 ± 9 | 77 ± 12 | 0.038 |
Body mass index | 24 ± 2 | 26 ± 3 | 0.017 |
HR at rest (bpm) | 72 ± 8 | 67 ± 10 | 0.321 |
Systolic blood pressure (mmHg) | 128 ± 12 | 144 ± 11 | 0.001 |
Diastolic blood pressure (mmHg) | 76 ± 6 | 78 ± 7 | 0.417 |
VO2max/bw (ml/(min·kg)) | - | 22 ± 6 | - |
MRI data | |||
Ejection fraction (%) | 64 ± 6 | 61 ± 7 | 0.213 |
LVEDV (ml) | 133 ± 21 | 126 ± 30 | 0.517 |
LVEDVI (ml/m2) | 74 ± 9 | 66 ± 13 | 0.079 |
LVESV (ml) | 48 ± 10 | 45 ± 15 | 0.548 |
LVESVI (ml/m2) | 27 ± 5 | 23 ± 7 | 0.194 |
LVMI (g/m2) | - | 52 ± 11 | - |
Positive LGE (number of patients) | - | 10 | - |
NYHA classification (number of patients) | |||
I | - | 16 | - |
II | - | 10 | - |
Medication (number of patients) | |||
Beta-blocker | 0 | 16 | - |
ACE-I | 0 | 7 | - |
ARB | 0 | 6 | - |
Calcium channel blocker | 0 | 9 | - |
Nitrate | 0 | 9 | - |
Aspirin | 0 | 22 | - |
Clopidogrel | 0 | 2 | - |
Warfarin | 0 | 1 | - |
Statin | 0 | 23 | - |
Diuretic | 0 | 2 | - |
ACE-I, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; HR, heart rate; LVEDV, left ventricular end diastolic volume; LVEDVI, left ventricular end diastolic volume index; LVESV, left ventricular end systolic volume; LVESVI, left ventricular end systolic volume index; LVMI, left ventricular mass index; NYHA, New York Heart Association; Positive LGE, late gadolinium enhancement in the LV myocardium; VO2max/bw, maximal oxygen consumption/body weight.