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. 2016 Aug 17;11(8):e0161391. doi: 10.1371/journal.pone.0161391

Table 1. Characteristics of the study population.

Control group Patients P-value
n = 10 n = 26
Age (y) 62 ± 11 68 ± 5 0.068
Gender (f/m) 7 / 3 10 / 16 -
Height (cm) 170 ± 8 170 ± 8 0.771
Weight (kg) 68 ± 9 77 ± 12 0.038
Body mass index 24 ± 2 26 ± 3 0.017
HR at rest (bpm) 72 ± 8 67 ± 10 0.321
Systolic blood pressure (mmHg) 128 ± 12 144 ± 11 0.001
Diastolic blood pressure (mmHg) 76 ± 6 78 ± 7 0.417
VO2max/bw (ml/(min·kg)) - 22 ± 6 -
MRI data
Ejection fraction (%) 64 ± 6 61 ± 7 0.213
LVEDV (ml) 133 ± 21 126 ± 30 0.517
LVEDVI (ml/m2) 74 ± 9 66 ± 13 0.079
LVESV (ml) 48 ± 10 45 ± 15 0.548
LVESVI (ml/m2) 27 ± 5 23 ± 7 0.194
LVMI (g/m2) - 52 ± 11 -
Positive LGE (number of patients) - 10 -
NYHA classification (number of patients)
I - 16 -
II - 10 -
Medication (number of patients)
Beta-blocker 0 16 -
ACE-I 0 7 -
ARB 0 6 -
Calcium channel blocker 0 9 -
Nitrate 0 9 -
Aspirin 0 22 -
Clopidogrel 0 2 -
Warfarin 0 1 -
Statin 0 23 -
Diuretic 0 2 -

ACE-I, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; HR, heart rate; LVEDV, left ventricular end diastolic volume; LVEDVI, left ventricular end diastolic volume index; LVESV, left ventricular end systolic volume; LVESVI, left ventricular end systolic volume index; LVMI, left ventricular mass index; NYHA, New York Heart Association; Positive LGE, late gadolinium enhancement in the LV myocardium; VO2max/bw, maximal oxygen consumption/body weight.