Skip to main content
. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: J Biomed Mater Res A. 2016 May 26;104(8):1853–1862. doi: 10.1002/jbm.a.35767

Figure 3. Healing rate was negatively affected by CFA-adjuvanted immunizations but not unadjuvanted peptide assemblies.

Figure 3

(a) In unsplinted 8 mm wounds in ob/ob mice, healing was delayed for CFA-ovaQ11/IFAovaQ11 compared to ovaQ11/ovaQ11, naïve/IFA-ovaQ11, and naïve/ovaQ11 (immunization/material in wound). The latter three groups did not differ significantly from each other. (b-d) Comparisons between wounds at day 10, 15, and 17. (e) Serum titers at the time of wounding at day 0 and day 7 after wounding, against ovaQ11 as measured by ELISA. All subpanels indicate mean with standard error. n=10 wounds per group (5 mice with 2 wounds per mouse). *p<0.05 comparing CFAovaQ11/IFAovaQ11 to ovaQ11/ovaQ11. ϕ p <0.05 comparing CFAovaQ11/IFAovaQ11 with naïve/IFAovaQ11. n.s, not statistically different.