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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: J Biomed Mater Res A. 2016 May 26;104(8):1853–1862. doi: 10.1002/jbm.a.35767

Figure 6. Cytokine Production of CD4+ cells: Th1 versus Th2.

Figure 6

Mice immunized against ovaQ11 received dermal wounds treated with Q11, ovaQ11 or IFA-ovaQ11 (5 mm wounds in C57BL/6 mice). T cells expressing IFNγ and IL4 were counted by flow cytometry. At Days 5 and 10 post-wounding, mice receiving Q11 or ovaQ11 in their wounds exhibited balanced Th1/Th2 T cell responses of similar amounts of IFNγ and IL4-producing cells, whereas mice receiving CFA-ovaQ11 had greater numbers of IFNγ-producing CD4+ T cells compared to IL4-producing CD4+ T cells, indicating a response that was comparatively more slanted towards Th1. n = 6 wounds per time point, 3 mice and 2 wounds per mouse. *p<0.05 by ANOVA with Tukey HSD post hoc test.