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. 2016 Aug 17;11(8):e0160778. doi: 10.1371/journal.pone.0160778

Table 1. Patient characteristics of patients with CDI and control patients.

Risk factors CDI patients (N = 79) Non-CDI control patients (N = 316)
N (%) N (%)
Age (mean ±SD) 67 (±17) 67 (± 16)
Male 50 (63) 178 (57)
Charlson comorbidity index*
0 16 (20) 64 (20)
1–2 34 (43) 156 (49)
3–4 20 (25) 66 (21)
≥ 5 9 (11) 29 (9)
Any antibiotic therapy (in 90 days)* 75 (95) 182 (58)
Antibiotic classes
Cephalosporins 62 (79) 95 (54)
Cephalosporins 1st generation 3 (4) 10 (3)
Cephalosporins 2nd and 3rd generation without SDD 25 (32) 54 (17)
Penicillins 38 (48) 82 (26)
Quinolones 32 (41) 62 (20)
Clindamycin 4 (5) 19 (6)
Metronidazole 19 (24) 17 (5)
SDD 38 (48) 49 (16)
Vancomycin 15 (19) 23 (7)
Carbapenems 10 (13) 27 (9)
Aminoglycosides 10 (13) 31 (10)
Macrolides 15 (19) 20 (6)
Proton pump inhibitors (-90 days)* 58 (73) 186 (59)
Number of ward transfers
0 20 (25) 140 (44)
1–2 39 (49) 150 (48)
≥ 3 20 (25) 26 (8)
Admission ICU 35 (44) 51 (16)
Length of stay before index date
≤ 5 days 14 (18) 129 (41)
6–10 days 11 (14) 70 (22)
11–25 days 28 (35) 67 (21)
> 25 days 26 (33) 50 (16)
Recent hospital admission (-90 days) 27 (34) 78 (25)
Admission to the same ward as an isolated CDI patient 51 (65) 234 (74)

* Data was missing for one patient.

SDD: selective decontamination of the digestive tract; ICU: intensive care unit