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(A) T1-weighted MPRAGE images with the volume of interest (20×20×25 mm3) for magnetic resonance spectroscopy (MRS) in the medial prefrontal cortex. (B) A representative 1H MR spectrum acquired with the SPECIAL sequence at 3T (TE/TR = 6/4000ms, number of averages = 148), the corresponding LCModel spectral fit, fit residual, macromolecules, baseline and individual metabolite fits including glutathione (GSH).
