Fig 4. Longitudinal multimodal imaging assessment of in vivo bladder tumor growth.

(A) BLI acquisition of MB49-luc tumor-bearing C57Bl/6 mice during local injury method 18 minutes after s.c. luciferin injection. BLI is expressed as the number of photons/sec; the graph is representing the increase in bioluminescence activity over time (n = 4, mean ± SD). (B) HRUS results expressed as tumor volume in mm³ over time after tumor cell implantation (n = 4, mean ± SD). (C) Serial PAI measurements showing average sO₂ values in tumor bearing mice (n = 4, mean ± SD).