Fig. 6.

Shape analysis of substantia nigra, subthalamic nucleus and red nucleus. Segmentations were affine-registered to MNI space prior to comparison. The tested contrast is Old > Young, where old includes both the middle-aged and elderly groups. The left column shows the difference in means between the two groups and the right column shows the associated p-values. In the right column, red-yellow colours indicate a significant local volume increase with age and blue colours indicate a decrease (p ≤ 0.025 for either the positive or negative contrast, corrected using TFCE).