Table 1.

Grading Scale used for assessment of isotretinoin associated cheilits

Clinical Criteria	Score Descriptions
Erythema	0-No involvement
	1- Mild erythema
	2 -Moderate erythema
	3-Severe erythema
Scale/Crust	0-No involvement
	1- Mild scale/crust
	2-Moderate scale/crust
	3-Severe scale/crust
Fissure	0-No fissures
	1-One fissure
	2-Two to four fissures
	3-Greater than four fissures
Commissures	0-No involvement
	1- Mild involvement: erythematous or scaly
	2 -Moderate involvem entherythematous and scaly, lichenified, mild fissuring
	3 -Severe involvement: more extensive erythema, scale, and lichenification or any of those with severe fissuring
Total Score	Ranges from 0 to 12